Journal Publications


Mack P, Nambiar RM. Carcinoma of the Stomach - A clinical study. Sing Med J 1985; 26:97-101

Mack OPP, Ng HN. Renal Trauma. A local experience. Med J Malaysia 1985; 40:312-316. 

Mack P, Nambiar RM. Leiomyoma of the caecum presenting as peritonitis. Med J Malaysia 1987; 42:299-301. 

Mack P, Jeppsson B, Widlus D, Hagerstrand I, Bengmark S. Combined intermittent dearterialisation and intraperitoneal 5-fluorouracil administration for liver tumours in the rat. Eur J Cancer Clin Oncol 1988; 24:909-913. 

Mack P, Ahren B, Jeppsson B, Zuxing K, Bengmark S. Influence of 2-deoxy-d-glucose and arterial ischaemia on glucose oxidative metabolism and growth of liver cancer. Eur J Cancer Clin Oncol 1988; 24:1433-1437. 

Mack P, Tranberg K-G, Stenram U, Jeppsson B, Widlus D, Bengmark S. RNA labelling with 3H-orotic acid and 3H-fluorouracil of rat liver tumour following transient hepatic arterial ischaemia. Eur J Surg Oncol 1988; 14:669-675. 

Mack P, Jeppsson B, Rajszys P, Kobayashi H, Asakawa H, Bengmark S. Retarding liver cancer growth in the rat by transient repeated hepatic dearterialisation. J Surg Res 1989; 46:123-128. 

Mack P, Ahren B, Jeppsson B, Bengmark S. Insulin response to a glucose challenge after transient hepatic dearterialisation in rat liver malignancy. J Surg Res 1989; 47:124-128. 

Mack P, Ahren B, Jeppsson B, Bengmark S. Glucose turnover in rats undergoing transient dearterialisation for liver malignancy. J Surg Res 1989; 47:447-452.
Asakawa H, Jeppsson B, Mack P, Hultberg B, Hagerstrand I. Acute ischemic liver failure in the rat - A reproducible model not requiring portal decompression. J Surg Res 1989; 46:123-128. 

Mack P. Pneumo-retroperitoneum associated with pneumatosis cystoides intestinalis. Ann Acad Med Sing 1989; 18:710-712. 

Mack P, Chellapa M, Sidhu DS, Iyer NKN. Acute omental infarction - A report of 6 cases. Ann Acad Med Sing 1989; 18:710-712.

Lim BH, Mack P, Chellappa M. Cholecysto-duodeno-colic fistula. A case report. Ann Acad Med Sing 1989; 18:296-297. 

Mack P, Nambiar R. Multiple splenic abscesses following pseudomonas sepsis. Ann Acad Med Sing 1989; 18:311-312. 

Ooi LLPJ, Mack P. Benign retroperitoneal neurilemmoma. A case report. Ann Acad Med Sing, 1990; 19:152-155. 

Mack P. A simple method of measuring cancer tissue metabolism. Ann Acad Med Sing 1990; 19:152-155. 

Ooi LLPJ, Yap TL, Rauff A, Mack P, Nambiar R. Splenic abscesses. A report of 7 cases. Aust NZ J Surg 1992; 2:13-18. 

Sundram FX, Mack P. Investigation of thyroid nodules using Technectium-99m sestamibi. Ann Acad Med Sing 1993; 22:560-562. 

Yu YQ, Tang ZY, Ma ZC, Zhou XD, Mack P. Resection of Segment VIII of liver for primary liver cancer. Arch Surg 1993; 128:224-227. 

Yu YQ, Xu DB, Zhou XD, Lu JZ, Tang ZY, Mack P. Experience with liver resection following hepatic arterial chemo-embolization for hepatocellular carcinoma.
Cancer 1993; 71:62-65. 

Mack P, Ooi L. Laparoscopic Cholecystectomy. A new milestone in surgery. Journal of New Medicine (Chinese) 1993; 4:154-158. 

Mack P, Ooi L. Complications of Laparoscopic cholecystectomy. J. of Clinical Surgery (Chinese) 1993; 1:3-5. 

Yang EB, Mack P, Cheng LY. Studies of epidermal growth factor (EGF) receptor in plasma membrane from rat liver and hepatoma tissue. Biochemistry and Molecular Biology International 1994; 33(2):221-228. 

Wang DF, Mack P, Cheng LY. Expression of MHC Class I antigen in Morris rat Hepatoma and normal liver. Cancer Letters 1994; 85:51-57. 

Oon CJ, Lim GK, Lee A, Ng LA, Mack P, Tan KS, Chia SC, Fock KM, Goh KT. Hepatitis E Virus infection in patients with hepatocellular carcinoma. Chemother Treat Rep. 

Chong MN, Mu KQ, Flyn D, Lee YT, Seah HS, Tan DTH, Mack P. Load Distribution in Parallel Ray Casting Algorithm. Concurrency: Practice & Experience, an International Journal published by John Wiley & Sons. 

Mack POP, Ng RTH, Song IC. Anaesthesia for animals in experimental research. Ann Acad Med Sing 1994; 23:470. 

Ooi LLPJ, Mack POP. Thoracoscopic Vagotomy for Peptic Ulcer Disease - Report of two cases. Ann Acad Med Sing 1994; 23:921-922. 

Ooi LLPJ, Low HC, Mack POP. Laparoscopic marsupialization of liver cysts. Aust NZ J Surg 1994; 64:262-263. 

Thomas J, Pillay P, Mack P. Video-assisted endoscopic thoracoscopic sympathectomy in the management of intractable palmar hyperhidrosis. Sing Med J 1994; 35:460-463. 

Chan HS, Ha XF, Ooi PJLL, Mack P, Soo KC. A prospective comparative study between conventional and laparoscopic cholecystectomy. Surg Endoscopy 1994; 8:613. 

Yang EB, Mack P, Cheng LY. Studies of epidermal growth factor (EGF) receptor in plasma membrane from rat liver and hepatoma tissue. Biochemistry and Molecular Biology International 1994; 33(2):221-228. 

Wang DF, Mack P, Cheng LY. Expression of MHC Class I antigen in Morris rat Hepatoma and normal liver. Cancer Letters 1994; 85:51-57. 

Sundram FX, Mack P. Evaluation of Thyroid nodules for malignancy using Tc99m Sestamibi. Nuclear Medicine Communications. 1995; 16:687-693. 

Lee CW, Mack P, Goh LB. “Overexpression of Nitrobenzylthioinosine-sensitive nucleoside transporter proteins in human colorectal, stomach and breast tumor tissues.” Proc Amer Assoc Cancer Res (1995) 36 p22. 

Chan HS, Ha XF, Ooi PJLL, Mack P. A Prospective Comparative Study between Conventional and Laparoscopic Cholecystectomy. Sing Med J 1995; 36:4-7. 

Goh LB, Mack P, Lee CW. Overexpression of Nitrobenzylthioinosine-sensitive nucleoside transporter proteins in human colorectal, stomach, liver and breast tumor tissues. Anti Cancer Research, 1995; 15:2575-2580. 

Chen XR, Luo T, Mack P. Laparoscopic repair of abdominal wall hernia. J. Clinical Surgery (Chinese) 1995; 3(3):119-120. 

Mack P. Endocrine Response following Laparoscopic and Open Cholecystectomy (Letter). Journal of Laparoendoscopic Surgery. 1995; 5:207-208. 

Ha XF, Mack P, Elnatan J, Smith D, Porter A, Goh C. Effect of high dose intra-tumoral rhTNF- on the growth of rat Morris Hepatoma. J Exp and Clin Cancer Res 1995; 14(4):365-371. 

Lin Y, Shi C-Y, Li B, Soo BH, Mohamed-Ali S, Wee A, Oon CJ, Mack P, Chan SH. Tumour-suppressor p53 and Rb genes in HBV-associated human hepatocellular carcinoma. Ann Acad Med Sing 1996; 25:22-30. 

Yang EB, Wang DF, Mack P, Cheng LY. Detection of EGF-induced EGF receptor degradation and tyrosine phosphorylation in intact cells. J. Biochem. Biophys. Methods 1996; 32: 97-108. 

Yang EB, Wang DF, Mack P, Cheng LY. EGF Receptor in Human Chang Liver and Hepatoma HepG2 Cells. Biochemistry and Molecular Biology International. 1996; 38:813-820. 

Yang EB, Wang DF, Mack P, Cheng LY. Genistein, a Tyrosine Kinase Inhibitor, reduces EGF-induced EGF receptor internalization and degradation in human hepatoma HepG2 Cells. Biochemical and Biophysical Research Communications. 1996; 224: 309-317. 

Mack P, Ha XF, Cheng LY. Suppression of tumour metabolism with Norcantharidin in Morris Hepatoma bearing rats. HPB Surgery 1996; 10:65-72. 

Ooi LLPJ, Koh J, Mack POP. Laparoscopic Hernia repair in Singapore - views from a cross-section of surgeons. Ann Acad Med Sing 1996; 25:643-645. 

Mack POP, Ngoi SS. Future Directions of Laparoscopic Surgery (Editorial) Ann Acad Med Sing 1996; 25:627-628. 

Yang, EB., Tang WY, Zhang K, Cheng, LY., and Mack POP. (1996) Norcantharidin inhibits growth of human hepatoma HepG2 tumor in Nude mice and prolongs host survival. Cancer Letters. 1997; 117: 93-98. 

Mack P. Palmar Hyperhidrosis - A social infirmity with a surgical relief. (Editorial) JAMA Southeast Asia. 1997; 13:7-8. 

P Mack, EB Yang, WY Tang, K Zhang, F Sundram, LY Cheng. An Experimental Study of the Anti-hepatoma Effect of Norcantharidin and its Myelo-stimulatory Function. Eur Surg Res 29 (Supp 1) : 76-77, 1997.

Oon CJ, Zhao Y, Lim GK, Mack P. Detection of HBsAG mutants in adult patients with HBsAg positive hepatocellular carcinoma in Singapore (Letter). Lancet. 

Zhang K, Mack P, Wong KP. Inhibition of various isoforms of rat liver glutathione S-transfereases by tannic acid and butein. Biochem Mol Biol Internal. 42: 701-710, 1997. 

Zhang K, Mack P, Wong KP. Conjugation of chlorambucil with GSH by GST purified from human colon adenocarcinoma cells and its inhibition by plant polyphenols. FASEB J. 11: A900, 1997. 

Zhang Kai, Er-Bin Yang, Wen-Ying Tang, Kim Ping Wong, Peter Mack. Inhibition of Glutathione Reductase by Plant Polyphenols. Biochemical Pharmacology 54: 1047-1053, 1997. 

EB Yang, DF Wang, LY Cheng, P Mack. Expression and Functions of Growth factors and growth factor receptors in liver cancer. The Cancer Journal Vol 10, no. 6, Nov-Dec 1997. 

Mack P, Cheng LY. The Thermal Activity of Normal and Malignant tissues - Microcalorimetric response of liver cancer to hepatic artery ligation, cryosurgery, Adriamycin and Norcantharidin. HPB Surgery, 1998; 11:75-86. 

Y. Zhou, POP Mack, EA Ling. Localisation of Nicotinamide Adenine Dinucleotide Phosphate-diaphorase reactivity and nitric oxide synthase immunoreactivity in the lumbosacral dorsal root ganglia in guinea pigs. J of Brain Research, 39 (1998) 2, 119-127. 

Kai Zhang, P. Mack, Wong KP. Glutathione-related mechanisms in cellular resistance to anticancer drugs (Review). International Journal of Oncology 12:871-882, 1998. 

Degenerative changes of afferent neurons in the lumbosacral dorsal root ganglia following complete urethral obstruction in guinea pigs. Zhou Y, Mack POP, Ling EA. Scand J Urol Nephrol. 1999 Feb;33(1):5-9. 

Yang EB, Zhao YN, Zhang K, Mack POP. Daphnetin, one of coumarin derivatives, is a protein kinase inhibitor. Biochem Biophys Res Commun 1999; 260: 682-5.

Zhou Y, Zhao YN, Yang EB, Ling EA, Wang Y, Hassouna MM, Mack POP. Induction of neuronal and inducible nitric oxide synthase in the motoneurons of spinal cord following transient abdominal aorta occlusion in rats. . J Surg Res 1999; 87: 185- 

Kai Zhang, EB Yang, KP Wong, P Mack. GSH, GSH-related enzymes and GS-X Pump in relation to sensitivity of human tumor cell lines to chlorambucial and adriamycin. International Journal of Oncology 14:861-867, 1999. 

EB Yang, Kai Zhang, Li YC, P Mack. Butein, a specific protein tyrosin kinase inhibitor. Biochemical and biophysical research communications. Vol 245, No. 2, 1998.

PKH Chow, TH Ng, D Heng, POP Mack. A simple method of blood pressure measurement in the pig using a neonatal cuff. Annals of Academy of Medicine, Singapore January 1999, vol 28, No. 1. 15-19. 

PKH Chow, TH Ng, M Chew, IC Song, HC Kee, POP Mack. A practical technique of colour Image analysis. Applications in experimental research. Annals of the Academy of Medicine, Singapore. Jan 1999, Vol. 28 No. 1, 155-158. 

Kai Z, Yang EB, Zhao YN, Wong KP, Mack P. Glutathione-related factors are not correlated with sensitivity of human tumour cells to actinomycin D. Cancer Letters 149 (2000) 213-220. 

Rong Y, Mack P. Apoptosis induced by hyperthermia in Dunn osteosarcoma cell line in vitro. Int. J. Hyperthermia 16: 19-27, 2000. 

Rong Y, Yang EB, Zhang K, Mack P. Quercetin-induced apoptosis in the Monoblastoid cell line U937 in vitro and the regulation of heat shock proteins expression. Anticancer Research 20: 4339-4346, 2000. 

Kai Z, Chew M, Yang EB, Wong KP, Mack P. Modulation of Cisplatin cytotoxicity and Cisplatin-induced DNA cross-links in human liver tumour cells by regulation of glutathione related mechanisms. Molecular Pharmacology 2001; 59:837-843. 

Yang EB, Yong JG, Zhang K, Yu ZC, Mack P. Inhibition of epidermal growth factor receptor tyrosine kinase by chalcone derivatives. Biochimica et Biophysica Acta 1550 (2001): 144-152. 

Shim WSN, Teh M, Mack POP, Ge RW. Inhibition of Angiopoietin-1 expression in tumor cells by an antisense RNA approach inhibited xenograft tumor growth in immunodeficient mice. Int. J. Cancer 94: (2001): 6-15. 

Jimmy Bok-Yan So, Khay-Guan Yeoh, shabbir Moochala, Naresh Chachlani, Jean Ho, Wai-Keong, Wong, Peter Mack, Peter M.Y. Goh. Serum pepsinogen levels in gastric cancer patients and their relationship with helicobackter pylori infection: a prospective study. Gastric Cancer (2002) 5: 228-232. 

Mack P. Patient Safety and Medical Errors – A Singapore Perspective. Singapore Medical Journal 2002; 43(5): 263-264. 

Shim, W. S. N, M. Teh, A. Bapna, I, Kim, G-Y Koh, P.Mack and R. Ge. Angiopoietin-1 Promotes Tumor Angiogenesis and Tumor Vessel Plasticity of Human Cervical Cancer in Mice. Experimental Cell Research, Vol 279, 299-309, 2002. 

Current status inthe Surgical Management of Adult Polycystic Liver Disease. YM Tan, LLPJ Ooi, POP Mack. Ann Acad Med Singapore 2002; 31:217-22. 

P. Mack. Utilitarian Ethics in Healthcare. International Journal of the Computer, The Internet and Management. 2004; 12(3): 63-72.

Yu-Meng Tan, Alexander Chung, Peter Mack, Pierce Chow, Lay-Way Khin, London L. Ooi. Role of Fenestration and Resection for Symptomatic Solitary Liver Cysts. ANZ. J. Surg, 2005; 577-580.


Book Publications

“Manual of Basic Operative Laparoscopic and Thoracoscopic Surgery Vol 1&2” Mack P, Ooi LL (ed), 1993. Forces Publications. Singapore. ISBN 981-00-4447-X

“Clinician's Guide to Experimental Surgery.” Mack P (ed). Image Medicus, Singapore 1994. ISBN 981-00-5972-8.

“Laparoscopic Surgery - Theory & Practice.” (Mandarin). Chen XR, Mack P, (ed). Yunnan Science and Technology Publications, China. 1995. ISBN7-5416-0719-3/R.109

“Regression Therapy in a Medical Practice” in: “Transforming the Eternal Soul”, Chapter 4, 2011, From the Heart Press, UK.

“Healing Deep Hurt Within” 2011, From the Heart Press. ISBN: 978-0-9567887-1-9